Antisense gene therapy using anti-k-ras and antitelomerase oligonucleotides in colorectal cancer
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چکیده
منابع مشابه
Antisense gene therapy using anti-k-ras and antitelomerase oligonucleotides in colorectal cancer.
AIM To test the efficacy of anti-k-ras and antitelomerase oligonucleotides for disabling colorectal cancer cell growth. MATERIAL AND METHODS An established human colorectal cancer cell line (SW 480, ATTC) was used. Oligodeoxiribonucleotides (ODNs) have a phosphorotioate modification to ensure intracellular intake. We used an antitelomerase ODN (Telp5) and two anti-k-ras ODNs (AS-KRAS and ISIS...
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ژورنال
عنوان ژورنال: Revista Española de Enfermedades Digestivas
سال: 2005
ISSN: 1130-0108
DOI: 10.4321/s1130-01082005000700002